Sachse lab

Electron cryomicroscopy of autophagy complexes

The Sachse group uses electron cryomicroscopy to study the structures of autophagy complexes to elucidate the mechanisms by which cells eliminate aberrant structures such as large protein aggregates. We are currently hosted by EMBL in Heidelberg (Germany).
autophagy double membrane
TMV cryo-EM reconstruction
spring single-particle helical reconstruction
Sachse group at EMBL
Sachse group